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The GATM gene is located on chromosome 15q21.1 and is composed of 13 exons that generate two alternatively spliced mRNAs that encode proteins of 423 amino acids (isoform 1) and 294 amino acids (isoform 2)

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While more human data is needed, its mechanism aligns with many principles of functional and longevity medicine namely, supporting mitochondria, reducing inflammation, and improving insulin sensitivity

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Anthropometric and laboratory evaluations Patient weight and height were measured using a calibrated scale after patients removed their shoes and any heavy clothing